ED & Premature Ejaculation Treatment Finder
Find Your Best Treatment Option
This tool helps you understand which treatment option might work best for your needs. Results are for informational purposes only and should not replace professional medical advice.
When you’re juggling an erectile‑function issue and premature ejaculation, the idea of taking two separate pills can feel like a hassle. Extra Super Avana is marketed as a single‑dose solution that bundles Dapoxetine and Avanafil together. But does the convenience outweigh potential drawbacks? Below we compare the combo with the most common alternatives, so you can decide which route fits your health profile and lifestyle.
What is Extra Super Avana?
Extra Super Avana is a prescription medication that contains two active ingredients in a fixed dose: 60 mg of dapoxetine (a short‑acting SSRI) for premature ejaculation and 200 mg of avanafil (a fast‑acting PDE5 inhibitor) for erectile dysfunction. The product is taken about 30 minutes before sexual activity and is designed to address both problems in one tablet, aiming to simplify timing and improve adherence.
How Dapoxetine Works
Dapoxetine belongs to the class of selective serotonin reuptake inhibitors (SSRIs). Unlike traditional SSRIs that stay in the system for weeks, dapoxetine is cleared quickly, producing a therapeutic effect within an hour and wearing off after about six hours. By increasing serotonin levels in the central nervous system, it prolongs the ejaculatory latency time, helping men last longer during intercourse.
How Avanafil Works
Avanafil is a phosphodiesterase type 5 (PDE5) inhibitor. It relaxes smooth muscle in the penile arteries, allowing more blood to flow in when sexual stimulation occurs. Avanafil’s onset is notably fast-often within 15 minutes-making it a popular choice for spontaneous activity. Its duration lasts roughly 6‑12 hours, shorter than some older PDE5 inhibitors.
Why Combine Them?
- Convenience: One pill replaces two, reducing the chance of missed doses.
- Co‑ordinated timing: Both agents work within the same window (30‑60 minutes), simplifying planning.
- Cost‑effectiveness: Some insurers bundle the combo under a single prescription, lowering out‑of‑pocket expenses.
However, bundling also means you can’t tweak the dose of each component independently, and any side‑effects from one drug affect the entire regimen.
Alternative Treatments for Premature Ejaculation
If you prefer not to lock yourself into a fixed‑dose combo, several proven alternatives exist:
- Priligy (dapoxetine‑only): Same ingredient, same quick‑acting profile, but you can pair it with any PDE5 inhibitor you like.
- Paroxetine or Sertraline: Traditional SSRIs taken daily; they delay ejaculation but require weeks to reach steady state and may cause more systemic side‑effects.
- Topical anesthetics (e.g., lidocaine‑prilocaine creams): Applied locally, they reduce penile sensitivity without systemic drug exposure.
- Behavioral techniques: The “stop‑start” and “squeeze” methods can be effective when practiced consistently.
All of these options let you adjust dosage or combine with any ED medication you prefer.
Alternative PDE5 Inhibitors for Erectile Dysfunction
Avanafil isn’t the only fast‑acting PDE5 inhibitor on the market. Consider these alternatives:
- Sildenafil (Viagra): Onset 30‑60 minutes, duration up to 5 hours. The most widely known and available generic.
- Tadalafil (Cialis): Onset 30 minutes, but can last up to 36 hours, enabling a “weekend pill” approach.
- Vardenafil (Levitra): Similar to sildenafil in timing, slightly stronger effect on some men.
- Lower‑dose options: Some brands offer 5 mg or 10 mg daily dosing, which may suit men who have frequent sexual activity.
Each has its own side‑effect profile (headache, flushing, visual changes) and drug‑interaction warnings, especially with nitrates.
Head‑to‑Head Comparison
| Attribute | Extra Super Avana (Dapoxetine + Avanafil) | Priligy + Sildenafil | Paroxetine + Tadalafil | Avanafil only |
|---|---|---|---|---|
| Mechanism | SSRI + PDE5 inhibitor | SSRI + PDE5 inhibitor | SSRI + PDE5 inhibitor (long‑acting) | PDE5 inhibitor only |
| Onset (PE) | 30‑60 min | 30‑60 min | 2‑3 weeks (daily) | N/A |
| Onset (ED) | 15‑30 min | 30‑60 min | 30‑60 min | 15‑30 min |
| Duration (ED) | 6‑12 h | 4‑6 h | 36 h | 6‑12 h |
| Dosing flexibility | Fixed combo | Separate pills - dose can be adjusted | Separate pills - dose can be adjusted | Single drug - no PE coverage |
| Common side‑effects | Headache, nausea, flushing | Same as combo + possible sildenafil‑specific visual changes | SSRI‑related sexual dysfunction, tadalafil‑related back pain | Headache, flushing |
| Cost (US 2025) | ~$80 per pack (30 tabs) | ~$75 (combined generic pills) | ~$90 (brand‑name SSRI + generic tadalafil) | ~$55 (generic avanafil) |
The table highlights that the combo saves you a pill but locks you into one dosage ratio. If you need more flexibility-say, a stronger ED dose on a weekend but a milder PE dose-the separate‑pill approach wins.
Choosing Between the Combo and Separate Options
Ask yourself these three questions:
- Do I need to adjust the PE dose independently? If yes, go separate.
- Do I prefer a fast‑acting ED pill for spontaneous encounters? Avanafil or the combo works, but avanafil alone is cheaper if PE isn’t an issue.
- Am I on any nitrate medication or have a heart condition? All PDE5 inhibitors share the same contraindication, so the decision hinges on PE treatment safety.
For men who value simplicity and have stable dosing needs, Extra Super Avana can be a practical choice. For those who want fine‑tuned control, separating dapoxetine from the PDE5 inhibitor is safer.
Safety, Interactions, and Contra‑indications
Both dapoxetine and avanafil are metabolized by the liver enzyme CYP3A4. Strong inhibitors (e.g., ketoconazole, grapefruit juice) can raise blood levels, increasing side‑effects. Nitrates (nitroglycerin, isosorbide dinitrate) are an absolute no‑go because the PDE5 blocker can cause dangerous blood‑pressure drops.
Common side‑effects across the board include headache, flushing, nasal congestion, and mild gastrointestinal upset. Dapoxetine may cause dizziness or insomnia, especially if taken too late in the evening. Patients with severe liver or renal impairment should discuss dose reductions with their physician.
How to Talk to Your Doctor
- Bring a list of all current meds-including over‑the‑counter supplements.
- Explain the frequency of both erectile difficulty and premature ejaculation.
- Ask specifically about the option to split the drugs versus using a combo.
- Discuss any cardiovascular history; your doctor will need to rule out nitrate use.
- Request a trial period with clear follow‑up to assess effectiveness and side‑effects.
Documenting your experience helps you and your prescriber decide whether to stay with the combo or switch to separate agents.
Quick Checklist Before Starting
- Confirm no nitrate medication in your regimen.
- Review liver and kidney function test results (if available).
- Know the exact timing-take the pill 30‑60 minutes before activity.
- Monitor for headache, flushing, or dizziness; report persistent symptoms.
- Schedule a follow‑up appointment after 2‑4 weeks.
Frequently Asked Questions
Can I take Extra Super Avana more than once a day?
No. Both dapoxetine and avanafil are designed for single‑dose use with a 24‑hour gap. Taking it twice can increase the risk of side‑effects, especially cardiovascular effects.
What if I have mild hypertension?
Mild, well‑controlled hypertension is not an automatic disqualifier, but you should discuss blood‑pressure control with your doctor. Some PDE5 inhibitors can cause a small, temporary drop in pressure.
Is the combo covered by insurance in New Zealand?
Pharmacy benefits vary. Some plans list the combo under “sexual health” and require prior authorisation. Check with your local PHARMAC or private insurer for the latest schedule.
Can I use a topical anesthetic with this combo?
Yes, but apply the cream at least 15 minutes before the oral dose to avoid overlapping sensations. Speak to a pharmacist to avoid excessive numbing.
What should I do if I experience a painful erection lasting more than 4 hours?
Seek emergency medical care immediately. This condition, called priapism, is rare with dapoxetine‑avanafil combos but can happen with any PDE5 inhibitor.
krishna chegireddy
October 24, 2025 AT 19:56Behold, the pharmaceutical overlords have stitched together Dapoxetine and Avanafil into a single pill, promising convenience while hiding the true cost. They claim simplicity, yet they lock you into a fixed dose that cannot be tweaked. This is a classic move to keep you dependent on one brand. The hidden agenda is clear: more profit, less control for the patient.
Melanie Vargas
October 24, 2025 AT 20:46Hey everyone 😊, let’s remember that each person’s body reacts differently, so what works for one might not work for another. If you’re thinking about trying the combo, talk to your doctor first and make sure it fits your health profile. Stay kind to yourself and support each other in these decisions! 🌟
Deborah Galloway
October 24, 2025 AT 21:53I totally get how overwhelming this can feel. The good news is you have options, and you don’t have to rush into a combo if you’re not comfortable. Keep a journal of how each medication affects you, it really helps when discussing with your clinician. You’ve got this, and we’re all here to cheer you on!
Charlie Stillwell
October 24, 2025 AT 23:00Alright, let’s cut the fluff – this “one‑pill‑does‑it‑all” hype is just marketing jargon wrapped in a shiny package. The pharmacokinetics of dapoxetine and avanafil don’t magically align for every user, and the side‑effect profile becomes a tangled mess. You’re basically buying a bundle that may not suit your dosage needs, and that’s a recipe for disappointment. 🤖💊 Plus, the cost is often inflated because of the brand‑name combo.
Buddy Bryan
October 25, 2025 AT 00:06When evaluating the Extra Super Avana combo, it’s essential to break down the pharmacodynamics of each component. Dapoxetine, as a short‑acting selective serotonin reuptake inhibitor, reaches peak plasma concentrations within an hour and clears quickly, which minimizes long‑term serotonergic side‑effects. Avanafil, on the other hand, has a rapid onset of action, often within 15 minutes, due to its high selectivity for the PDE5 enzyme and low affinity for other phosphodiesterases. This dual action can be advantageous for men who require spontaneity, but the fixed ratio of 60 mg dapoxetine to 200 mg avanafil limits titration flexibility. If a patient experiences excessive nausea from dapoxetine, the only recourse is to discontinue the entire combo, losing the benefit of avanafil. Conversely, if a higher dose of avanafil is needed for severe erectile dysfunction, the patient cannot simply increase the avanafil component without also raising dapoxetine exposure, which may increase the risk of dizziness or insomnia. From a cost perspective, the combo can be cheaper when insurance bundles the prescription, yet the out‑of‑pocket price often remains higher than generic separate agents. Clinicians should also consider drug‑drug interactions; both agents are metabolized by CYP3A4, so strong inhibitors like ketoconazole or even grapefruit juice can elevate plasma levels dramatically, raising the chance of adverse events. In patients with cardiovascular comorbidities, the absolute contraindication with nitrates remains unchanged, regardless of the formulation. Monitoring liver function is prudent because both drugs are hepatically cleared, and dose adjustments may be necessary in hepatic impairment. Finally, patient preference for a single‑tablet regimen should be weighed against the desire for individualized dosing and the potential for side‑effect management. A trial period of 2‑4 weeks with documented symptom scores can help determine whether the combo or separate agents better meet the patient’s therapeutic goals.
Jonah O
October 25, 2025 AT 01:13Yo, have you ever thought that they uss the same lab to hide the real data? I mean, every time they push a new combo, the fine print gets foggy. Some secret formulators might be playing with the dosage ratios like a lab rat. Stay woke, because the truth is always buried under a layer of marketing fluff.
Aaron Kuan
October 25, 2025 AT 02:20Colors bleed, pills merge, risk glints.
Corrine Johnson
October 25, 2025 AT 03:26Honestly, the very notion of a "one‑size‑fits‑all" sexual health solution is fundamentally flawed, overly simplistic, and reeks of commercial exploitation; you cannot possibly expect a single dosage ratio to address the nuanced spectrum of erectile dysfunction severity, partnered intimacy dynamics, and premature ejaculation variability, all while maintaining a tolerable side‑effect profile for every individual, which, frankly, demonstrates a lack of clinical empathy and a gross misunderstanding of personalized medicine.
Jennifer Stubbs
October 25, 2025 AT 04:33The critique is valid in highlighting the inflexibility of the combo, yet it overlooks the potential adherence benefits for patients who struggle with multiple prescriptions. While the blanket judgment may deter some, a balanced view recognizes that for a subset of men, especially those with stable dosing needs, the convenience could outweigh the lack of titration. Ultimately, decision‑making should be driven by individualized risk‑benefit analysis rather than blanket condemnation.